A pilot randomized controlled trial to explore cognitive and emotional effects of probiotics in fibromyalgia
Calculations of key parameters of the mitochondrial function were performed, consisting of basal respiration (BR, OCR initial OCR rot/AA ), ATP production (ATP, OCR initial - OCR oligo ), proton leak (PL, OCR oligo OCR rot/AA ), maximal respiration (MR, OCR FCCP OCR rot/AA ), spare respiratory capacity (SRC, OCR FCCP - OCR initial ), spare respiratory capacity [%] (SRCP, MR/BR*100), non-mitochondrial respiration rate (NMRR, OCR rot/AA ), and coupling efficiency [%] (CE, ATP/BR*100)
Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome
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The only limiting factors are typically adverse effects that increase with higher doses or the impracticality (physically or financially) of taking excessive amounts of these treatments
